Morbidity and mortality in the Systolic Hypertension in the Elderly Program (SHEP) pilot study.

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Morbidity and mortality in the Systolic Hypertension in the Elderly Program (SHEP) pilot study.

The pilot study of the Systolic Hypertension in the Elderly Program was a randomized, double-blind, placebo-controlled trial of drug therapy for isolated systolic hypertension. It followed 551 elderly participants with untreated blood pressures of greater than 160/less than 90 mm Hg for an average of 34 months. Mean age of the participants was 72 years; 63% were women, and 82% were white. Pretr...

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Systolic Hypertension in the Elderly Program (SHEP). Part 5: Baseline blood pressure and pulse rate measurements.

In preparation for blood pressure determination, the midarm circumference was measured on the bared right upper arm, with the participant standing. The appropriate size cuff was then selected from a chart of arm circumference measurements and corresponding cuff sizes (Table 5.1) (SHEP Blood Pressure Manual). Measurements of blood pressure and pulse rate were performed only after the participant...

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Stroke in the elderly treated for systolic hypertension (SHEP) part II--mortality.

This was a multicenter, randomized, placebo-controlled clinical trial of a stepped anti_hypertensive regimen in selected screenees age 60 years and older, drawn from a community-based ambulatory population in 16 tertiary medical centers in the U.S. From the pool of 447,921 potential candidates, 4,736 were selected as suitable candidates on the basis of informed consent and confirmed systolic bl...

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Atrial fibrillation and isolated systolic hypertension: the systolic hypertension in the elderly program and systolic hypertension in the elderly program-extension study.

We performed a post hoc analysis of the Systolic Hypertension in the Elderly Program database to assess the incidence of atrial fibrillation in the elderly hypertensive population, its influence on cardiovascular events, and whether antihypertensive treatment can prevent its onset. The Systolic Hypertension in the Elderly Program was a double-blind placebo-controlled trial in 4736 subjects with...

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ژورنال

عنوان ژورنال: Stroke

سال: 1989

ISSN: 0039-2499,1524-4628

DOI: 10.1161/01.str.20.1.4